Differential GPS surveys done in 2014 have confirmed that Mount Isto is the highest point in the Brooks Range, the North Slope Borough, and the Arctic National Wildlife Refuge, as well as a peak with world-class prominence and isolation. Mount Chamberlin, 25 miles to the west, was long thought to be higher or at least a contender, but Isto is now known to be 70 feet higher.
Mount Isto is in a somewhat remote part of the Brooks Range. It lies near the headwaters of some popular rafting rivers that flow north to the Arctic, and its base could possibly be accessed by a bush plane landing on a gravel bar. The climbing is, by all accounts, relatively gentle by Alaskan standards.